Objective: Introduction: Patients, undergoing treatment in the intensive care units (ICU) often (51&) suffer from the infections and predominantly (71&) receive antibiotics. The aim: We aimed to review scientific literature, that highlights recent developments in etiology and emerge problems of struggling infectious complications in critically ill.
Patients and methods: Materials and methods: We performed a search of literature from 1994 to 2018 years in Google Scholar, PubMed, MedLine, Embase, Cochrane. Data from 70 articles devoted and books to the problem were accumulated and synthesized in the article.
Conclusion: Conclusion: Antibiotic resistance is considered as challenging problem in medicine throughout the world. Strains of S.aureus with antibiotic resistance have acquired genes of resistance to methicillin, vancomycin. There was registered high occurrence of E. coli, K. pneumonia, Acinetobacter spp. and P. aeruginosa, which produce extended spectrum β-lactamases, carbapenemases and have a rising levels of resistance to aminoglycosides and fluoroquinolones.
Keywords: antibiotics; antimicrobial prevention; critically ill; infectious complications; resistance.