Cryogels of carboxyalkylchitosans as a universal platform for the fabrication of composite materials

Svetlana Bratskaya; Yuliya Privar; Arseny Slobodyuk; Dariya Shashura; Dmitry Marinin; Alexandr Mironenko; Veniamin Zheleznov; Alexander Pestov

doi:10.1016/j.carbpol.2018.12.094

Cryogels of carboxyalkylchitosans as a universal platform for the fabrication of composite materials

Carbohydr Polym. 2019 Apr 1:209:1-9. doi: 10.1016/j.carbpol.2018.12.094. Epub 2019 Jan 3.

Authors

Svetlana Bratskaya¹, Yuliya Privar², Arseny Slobodyuk², Dariya Shashura², Dmitry Marinin², Alexandr Mironenko², Veniamin Zheleznov², Alexander Pestov³

Affiliations

¹ Institute of Chemistry Far Eastern Branch of the Russian Academy of Sciences, 159, prosp.100-letiya Vladivostoka, 690022 Vladivostok, Russia. Electronic address: sbratska@ich.dvo.ru.
² Institute of Chemistry Far Eastern Branch of the Russian Academy of Sciences, 159, prosp.100-letiya Vladivostoka, 690022 Vladivostok, Russia.
³ I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 20, S. Kovalevskoy str., Yekaterinburg 620990, Russia.

PMID: 30732787
DOI: 10.1016/j.carbpol.2018.12.094

Abstract

Here we report a new simple method for fabrication of supermacroporous beads and monoliths via cross-linking of carboxyalkylated chitosan derivatives with hexamethylene diisocyanate in aqueous solution at subzero temperature. These materials provide high filtration rate and good mass-transfer that in combination with high binding capacity toward metal ions allows their application as a universal platform for fabrication of composite catalysts, sorbents, and metal-affine chromatography stationary phases. Using N-(2-carboxyethyl)chitosan (CEC), we have demonstrated that optimum chitosan carboxylation degree for cryogels synthesis is close to 1.0. Cu(II)-chelated CEC cryogels have shown high efficiency as metal-affinity sorbents for ciprofloxacin recovery. Co(II)-chelated CEC cryogels have been used for fabrication of Co(II) ferrocyanide-containing composite with the distribution coefficient for ¹³⁷Cs of 140,000 ml/g and the adsorption capacity of ˜1 mmol/g. Composite Pd-catalysts supported on CEC cryogel provided tenfold higher reaction rate in 4-nitrophenol reduction in comparison with Pd-catalyst supported on chitosan beads.

Keywords: Carboxyalkylchitosan; Catalysis; Ciprofloxacin; Cryogel; Ferrocyanide; Metal-chelate sorbent.