Uremic lion face syndrome

J Bras Nefrol. 2019 Apr-Jun;41(2):304-305. doi: 10.1590/2175-8239-JBN-2018-0198. Epub 2019 Jan 21.
[Article in English, Portuguese]

Abstract

Mineral bone disorder is a common feature of chronic kidney disease. Lion face syndrome is rare complication of severe hyperparathyroidism in end-stage renal disease patients, which has been less commonly reported due to dialysis and medical treatment advances in the last decade. The early recognition of the characteristic facial deformity is crucial to prompt management and prevent severe disfigurement. The authors present a rare case of severe hyperparathyroidism presenting with lion face syndrome and bone fractures.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bone Density
  • Bone Density Conservation Agents / therapeutic use
  • Calcium / therapeutic use
  • Chronic Kidney Disease-Mineral and Bone Disorder / complications*
  • Ergocalciferols / therapeutic use
  • Female
  • Fractures, Bone / diagnosis
  • Humans
  • Hyperostosis Frontalis Interna / diagnosis*
  • Hyperostosis Frontalis Interna / etiology*
  • Hyperostosis Frontalis Interna / surgery
  • Hypocalcemia / drug therapy
  • Hypocalcemia / etiology
  • Kidney Failure, Chronic / complications*
  • Parathyroidectomy / adverse effects
  • Postoperative Complications / drug therapy
  • Renal Dialysis
  • Teriparatide / therapeutic use
  • Treatment Outcome

Substances

  • Bone Density Conservation Agents
  • Ergocalciferols
  • Teriparatide
  • paricalcitol
  • Calcium