1 Departments of Critical Care Medicine and Pediatrics, UPMC Children's Hospital of Pittsburgh and University of Pittsburgh School of Medicine; and Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh PA Departments of Critical Care Medicine, Pediatrics, and Clinical and Translational Science Institute, UPMC Children's Hospital of Pittsburgh and University of Pittsburgh School of Medicine; Department of Critical Care Medicine Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh PA.