How Live Attenuated Vaccines Can Inform the Development of Broadly Cross-Protective Influenza Vaccines

J Infect Dis. 2019 Apr 8;219(Suppl_1):S81-S87. doi: 10.1093/infdis/jiy703.

Authors

Rajeev Rudraraju¹, Francesca Mordant¹, Kanta Subbarao^{1

2}

Affiliations

¹ Department of Microbiology and Immunology, University of Melbourne.
² World Health Organization Collaborating Centre for Reference and Research on Influenza, Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.

No abstract available

Keywords: influenza; live attenuated influenza vaccine; pandemic; prime-boost; seasonal.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Animals
Antibodies, Viral / immunology
Broadly Neutralizing Antibodies / immunology
Child
Child, Preschool
Cross Protection / immunology*
Hemagglutinin Glycoproteins, Influenza Virus / immunology
Humans
Immunity, Mucosal / immunology
Influenza A virus / immunology*
Influenza A virus / isolation & purification
Influenza B virus / immunology
Influenza B virus / isolation & purification
Influenza Vaccines / immunology*
Influenza, Human / epidemiology
Influenza, Human / prevention & control*
Neuraminidase / immunology
Orthomyxoviridae Infections / immunology
Orthomyxoviridae Infections / virology
Pandemics / prevention & control*
Vaccination
Vaccines, Attenuated / immunology*
Vaccines, Inactivated / immunology
Virus Shedding / immunology

Substances

Antibodies, Viral
Broadly Neutralizing Antibodies
Hemagglutinin Glycoproteins, Influenza Virus
Influenza Vaccines
Vaccines, Attenuated
Vaccines, Inactivated
Neuraminidase