The influence of adalimumab on the expression profile of mRNAs and miRNAs related to the IL-12 and IL-23 signal paths

J Eur Acad Dermatol Venereol. 2019 May;33(5):e198-e199. doi: 10.1111/jdv.15463. Epub 2019 Mar 3.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adalimumab / pharmacology*
  • Anti-Inflammatory Agents / pharmacology*
  • Cells, Cultured
  • Fibroblasts
  • Gene Expression / drug effects*
  • Humans
  • Interleukin-12 / metabolism
  • Interleukin-23 / metabolism
  • Interleukin-6 / genetics
  • Leptin / genetics
  • MicroRNAs / metabolism
  • Psoriasis / drug therapy*
  • Psoriasis / genetics
  • RNA, Messenger / metabolism
  • Receptors, Notch / genetics
  • Signal Transduction
  • Transcription Factor HES-1 / genetics
  • Transcription, Genetic / drug effects

Substances

  • Anti-Inflammatory Agents
  • IL6 protein, human
  • Interleukin-23
  • Interleukin-6
  • LEP protein, human
  • Leptin
  • MicroRNAs
  • RNA, Messenger
  • Receptors, Notch
  • Transcription Factor HES-1
  • HES1 protein, human
  • Interleukin-12
  • Adalimumab