The molecular diversity scope of 4-hydroxycoumarin in the synthesis of heterocyclic compounds via multicomponent reactions

Ghodsi Mohammadi Ziarani; Razieh Moradi; Tahereh Ahmadi; Parisa Gholamzadeh

doi:10.1007/s11030-019-09918-7

The molecular diversity scope of 4-hydroxycoumarin in the synthesis of heterocyclic compounds via multicomponent reactions

Mol Divers. 2019 Nov;23(4):1029-1064. doi: 10.1007/s11030-019-09918-7. Epub 2019 Jan 29.

Authors

Ghodsi Mohammadi Ziarani¹, Razieh Moradi², Tahereh Ahmadi³, Parisa Gholamzadeh³

Affiliations

¹ Department of Chemistry, Alzahra University, Tehran, Iran. gmohammadi@alzahra.ac.ir.
² Department of Chemistry, Alzahra University, Tehran, Iran. moradi3452@yahoo.com.
³ Department of Chemistry, Alzahra University, Tehran, Iran.

PMID: 30697671
DOI: 10.1007/s11030-019-09918-7

Abstract

4-Hydroxycoumarins are some of the most versatile heterocyclic scaffolds and are frequently applied in the synthesis of various organic compounds. 4-Hydroxycoumarin-based compounds are important among heterocyclic structures due to their biological and pharmaceutical activities. In this study, we provide an overview on the recent applications of 4-hydroxycoumarin in multicomponent reactions for the synthesis of various heterocyclic compounds during the time period of 2015-2018.

Keywords: 4-Hydroxycoumarin; Heterocycles; Multicomponent reaction; Synthesis.

Publication types

Review

MeSH terms

4-Hydroxycoumarins / chemistry*
Pyrans / chemistry
Pyrimidines / chemistry
Pyrrolidines / chemistry

Substances

4-Hydroxycoumarins
Pyrans
Pyrimidines
Pyrrolidines