[Surgical Treatment for Liver Metastases of Gastric Cancer]

Gan To Kagaku Ryoho. 2018 Dec;45(13):2270-2272.
[Article in Japanese]

Abstract

At present, there is no apparent consensus about the indications for hepatectomy for liver metastases of gastric cancer. In this study, we identified factors of poor prognosis to investigate the indications for hepatectomy in 24 cases of hepatectomy for liver metastases of gastric cancer at our hospital during a period from August 2001 to September 2017. The 1-, 3-, and 5- year survival rates in all 24 cases were 63%, 21%, and 17%, respectively. Single variable analysis revealed that significant factors of poor prognosis were 3 or more liver metastases, synchronous liver metastasis, and positive surgical margin. Multivariable analysis revealed that significant independent factors of poor prognosis were synchronous liver metastases(HR 4.71, 95%CI: 1.08-21.79, p=0.040)and positive surgical margin(HR 5.95, 95%CI: 1.56-25.81, p=0.009). These findings indicated that, in cases of metachronous tumors and negative surgical margin, favorable prognosis can be expected following surgical resection for liver metastases of gastric cancer.

MeSH terms

  • Hepatectomy
  • Humans
  • Liver Neoplasms* / secondary
  • Liver Neoplasms* / surgery
  • Prognosis
  • Retrospective Studies
  • Stomach Neoplasms* / pathology
  • Survival Rate