In this cohort of 51 patients managed with retained "destination spacers" after the resection of infected joint prostheses, the presence of preoperative sinus drainage was significantly associated with reinfection. Chronic antimicrobial suppression after destination-spacer retention did not significantly prevent reinfections.
Keywords: antibiotic spacer retention; antimicrobial suppression; periprosthetic joint infection; total hip arthroplasty; total knee arthroplasty.
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