Use of animal models in peripheral nerve surgery and research

Neurol India. 2019 Jan-Feb;67(Supplement):S100-S105. doi: 10.4103/0028-3886.250706.

Abstract

Animal models are widely used in research of peripheral nerve injury and regeneration, since there are only minor differences in the anatomy of peripheral nerves and the physiology of nerve regeneration between the humans and animals. Animal models, especially rodents, are widely used for this purpose. This narrative review provides a brief overview of the role of animal models in peripheral nerve surgery and research.

Keywords: Animal models; peripheral nerve research; peripheral nerve surgery; primates; rodents.

Publication types

  • Review

MeSH terms

  • Animals
  • Disease Models, Animal*
  • Humans
  • Nerve Regeneration*
  • Neuronal Plasticity
  • Neurosurgical Procedures / education
  • Peripheral Nerve Injuries / physiopathology*
  • Peripheral Nerve Injuries / surgery*
  • Translational Research, Biomedical