Implementation of public health genomics and applications to public health dentistry

J Public Health Dent. 2020 Mar:80 Suppl 1:S37-S42. doi: 10.1111/jphd.12307. Epub 2019 Jan 28.

Abstract

National and state public health genomics efforts exist to effectively and responsibly translate genome-based knowledge to improve population health and reduce health disparities. Over the past two decades, public health genomics efforts have utilized the core public health functions of assessment, policy development, and assurance. Current evidence for a small number of genomic applications suggests that many lives could be saved if these were implemented in recommended populations. With the drastic increase in new genetic tests and technologies, multidisciplinary public health genomics efforts that should include public health dentistry are of greater importance. There is a need to integrate public health dentistry in efforts to increase use of evidence-based genomic tests and services to improve health outcomes. Additionally, public health genomic efforts also are utilized to promote awareness about the insufficient evidence of the validity, utility and ethical, legal, and social implications for the vast majority of genomic tests. This is demonstrated by a recent genetic testing policy statement and educational resources from the American Dental Association. These organizational efforts should be considered in other realms of public health genomics to ensure that only genetic tests and preventive services with sufficient evidence for use are being implemented in clinical and public health.

Keywords: dental; genetic counseling; implementation; oral health; precision medicine; public health; public health dentistry; public health genomics.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Genetic Testing
  • Genomics*
  • Public Health Dentistry
  • Public Health*
  • United States