The impact of today's optimal planting dates on sudden death syndrome (SDS) (caused by Fusarium virguliforme) development and soybean yield loss are not yet well understood. Field trials established in Hancock, Wisconsin during 2013 and 2014 investigated interactions between planting date and cultivar on SDS development and soybean yield. In 2013, disease index (DX) levels differed among cultivars, but results showed no difference between the 6 May and 24 May planting dates. Significantly lower DX levels were observed for the 17 June date. Greatest yields were found in the 6 May planting date, and yield losses were 720 (17%), 770 (20%), and 400 kg ha-1 (12%) for the 6 May, 24 May, 17 and June planting dates, respectively. In 2014, cultivars again differed for DX, but results showed highest DX levels in the 5 May planting date, with little disease observed in the 22 May and 11 June dates. Yield losses were 400 (12%) and 270 kg ha-1 (9%) for the 5 May and 22 May dates, respectively, but no difference was found in the 11 June date. Despite the most symptom development, these results suggest early May planting coupled with appropriate cultivar selection provides maximum yield potential and profitability in Wisconsin.