Encapsulation of Thymol in Biodegradable Nanofiber via Coaxial Eletrospinning and Applications in Fruit Preservation

J Agric Food Chem. 2019 Feb 13;67(6):1736-1741. doi: 10.1021/acs.jafc.8b06362. Epub 2019 Feb 5.

Abstract

The application of the nanofiber film in the field of food preservation was an emerging research direction in recent years. With the functionalization of nanofibers, the quality and safety of food can be better guaranteed. In the present work, thymol as an antibacterial agent was encapsulated into poly(lactide- co-glycolide) to form core-shell nanofibers by coaxial electrospinning. With such a core-shell nanofiber film, thymol can be slowly released to headspace between food and the nanofiber film, inhibiting the growth of bacteria on the surface of food. The morphology and core-shell structure of nanofibers were confirmed by scanning electron microscopy and transmission electron microscopy. The antibacterial and fruit preservation abilities of the nanofiber film were tested on strawberries. Studies have shown that it can effectively inhibit the growth of bacteria, fungi, and yeast and extend the shelf life of fruit. This novel antibacterial packaging material with excellent biocompatibility, biodegradability, and good sustained release performance would have a broad application prospect in the field of food preservation.

Keywords: PLGA; coaxial eletrospinning; fruit preservation; thymol.

Publication types

  • Evaluation Study

MeSH terms

  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / pharmacology
  • Bacteria / drug effects
  • Bacteria / growth & development
  • Drug Compounding
  • Electrochemical Techniques
  • Food Packaging / instrumentation
  • Food Preservation / instrumentation
  • Food Preservation / methods*
  • Food Storage
  • Fragaria / chemistry*
  • Fragaria / microbiology
  • Fruit / chemistry*
  • Fruit / microbiology
  • Nanofibers / chemistry*
  • Polyglactin 910 / chemistry
  • Thymol / chemistry*
  • Thymol / pharmacology

Substances

  • Anti-Bacterial Agents
  • Polyglactin 910
  • Thymol