Bicuspid aortic valve endocarditis caused by Gemella sanguinis: Case report and literature review

J Infect Public Health. 2019 May-Jun;12(3):304-308. doi: 10.1016/j.jiph.2019.01.001. Epub 2019 Jan 19.

Abstract

Gemella species are catalase-negative, facultative anaerobic, Gram-positive cocci, which are part of the human oral microbiome and may occasionally cause systemic infections. Infective endocarditis (IE) has been reported as the most common infection caused by Gemella species. We report the first case of IE due to Gemella sanguinis in Greece, in a patient with bicuspid aortic valve and review the available literature. The patient was successfully treated with antibiotics and aortic valve replacement.

Keywords: Aortic regurgitation; Bicuspid aortic valve; Gemella sanguinis; Infective endocarditis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • Aortic Valve*
  • Diagnosis, Differential
  • Echocardiography
  • Endocarditis, Bacterial / diagnosis*
  • Endocarditis, Bacterial / diagnostic imaging
  • Endocarditis, Bacterial / drug therapy
  • Endocarditis, Bacterial / surgery
  • Gemella / isolation & purification*
  • Gram-Positive Bacterial Infections / diagnosis*
  • Gram-Positive Bacterial Infections / diagnostic imaging
  • Gram-Positive Bacterial Infections / drug therapy
  • Gram-Positive Bacterial Infections / surgery
  • Greece
  • Heart Valve Prosthesis Implantation
  • Humans
  • Infusions, Intravenous
  • Male
  • Young Adult

Substances

  • Anti-Bacterial Agents