Motor behavior unmasks residual cognition in disorders of consciousness

Ann Neurol. 2019 Mar;85(3):443-447. doi: 10.1002/ana.25417. Epub 2019 Feb 10.

Abstract

Disorders of consciousness (DOC) are a common consequence of severe brain injuries, and clinical evaluation is critical to provide a correct diagnosis and prognosis. The revised Motor Behavior Tool (MBT-r) is a clinical complementary tool aiming to identify subtle motor behaviors that might reflect residual cognition in DOC. In this prospective study including 30 DOC patients in the early stage after brain injury, we show that the revised MBT-r has an excellent inter-rater agreement and has the ability to identify a subgroup of patients, underestimated by the Coma Recovery Scale-Revised, showing residual cognition and a subsequent recovery of consciousness. ANN NEUROL 2019;85:443-447.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Brain Injuries / complications
  • Brain Injuries / physiopathology*
  • Brain Injuries, Traumatic / complications
  • Brain Injuries, Traumatic / physiopathology
  • Cognition*
  • Coma / etiology
  • Coma / physiopathology
  • Consciousness Disorders / diagnosis
  • Consciousness Disorders / etiology
  • Consciousness Disorders / physiopathology*
  • Female
  • Glasgow Coma Scale
  • Glasgow Outcome Scale
  • Humans
  • Hypoxia, Brain / complications
  • Hypoxia, Brain / physiopathology
  • Intracranial Hemorrhages / complications
  • Intracranial Hemorrhages / physiopathology
  • Male
  • Middle Aged
  • Motor Activity*
  • Persistent Vegetative State / etiology
  • Persistent Vegetative State / physiopathology
  • Prospective Studies
  • Stroke / complications
  • Stroke / physiopathology