Study of arterial stiffness in patients with an acute coronary event and chronic obstructive pulmonary disease confirmed by spirometry

P Almagro; E Acosta; A Navarro; M F Murillo; S Valdivielso; A de la Sierra

doi:10.1016/j.rce.2018.08.007

Study of arterial stiffness in patients with an acute coronary event and chronic obstructive pulmonary disease confirmed by spirometry

Rev Clin Esp (Barc). 2019 Jun-Jul;219(5):251-255. doi: 10.1016/j.rce.2018.08.007. Epub 2019 Jan 16.

[Article in English, Spanish]

Authors

P Almagro¹, E Acosta², A Navarro³, M F Murillo², S Valdivielso⁴, A de la Sierra²

Affiliations

¹ Unidad de Pacientes Crónicos Complejos, Departamento de Medicina Interna, Hospital Universitario Mútua Terrasa, Universidad de Barcelona, Terrasa, Barcelona, España; Departamento de Medicina Interna, Hospital Universitario Mútua Terrasa, Universidad de Barcelona, Terrasa, Barcelona, España. Electronic address: palmagro@mutuaterrassa.es.
² Departamento de Medicina Interna, Hospital Universitario Mútua Terrasa, Universidad de Barcelona, Terrasa, Barcelona, España.
³ Servicio de Neumología, Hospital Universitario Mútua Terrasa, Universidad de Barcelona, Terrasa, Barcelona, España.
⁴ Servicio de Cardiología, Hospital Universitario Mútua Terrassa, Universidad de Barcelona, Terrasa, Barcelona, España.

PMID: 30660321
DOI: 10.1016/j.rce.2018.08.007

Abstract

Background and objectives: Chronic obstructive pulmonary disease (COPD) worsens the prognosis for patients with an acute coronary event (ACE) treated with percutaneous coronary intervention. Objective To assess the effect of COPD on arterial stiffness in patients with an ACE.

Methods: The study included patients with an ACE treated with percutaneous coronary intervention. At 1 month, postbronchodilation spirometry was performed, and arterial stiffness and markers of myocardial damage (troponin T and ProBNP) were measured.

Results: We included 68 patients, 33% of whom had COPD (59% undiagnosed). The patients with COPD presented higher arterial stiffness values after adjusting for age and blood pressure readings. The troponin T and ProBNP levels were higher in the patients with COPD.

Conclusions: Arterial stiffness is greater in patients with an ACE if they have concomitant COPD. These findings can help explain the poorer prognosis of patients with both conditions.

Keywords: Arterial stiffness; Cardio-ankle vascular index; Cardiopatía isquémica; Chronic obstructive pulmonary disease; Enfermedad pulmonar obstructiva crónica; Intervención coronaria percutánea; Ischaemic heart disease; Percutaneous coronary intervention; Pulse wave velocity; Rigidez arterial; Velocidad de onda de pulso; Índice vascular corazón-tobillo.