Screening Program of Abdominal Aortic Aneurysm

Angiology. 2019 May;70(5):407-413. doi: 10.1177/0003319718824940. Epub 2019 Jan 17.

Abstract

In Europe, the prevalence of abdominal aortic aneurysms (AAAs) in the elderly population (≥65 year old) has declined in the past decades to <4%. Aneurysmal degeneration of the aorta is a serious and potentially life-threatening vascular disease. Abdominal aortic aneurysms typically develop subclinically and often only become symptomatic when complicated by impending rupture. Most AAAs are discovered incidentally while investigating for an unrelated pathology. Ruptured AAA is the tenth leading cause of death in Belgium (0.32% of all deaths in 2014). Health-care providers have emphasized the importance of early detection of AAA and elective repair when the rupture risk outweighs operative risk (usual diameter threshold of 55 mm). Routine AAA screening programs, consisting of a single abdominal ultrasonography at the age of 65 years, aim to reduce the number of AAA-related deaths. Does population-based ultrasound screening for AAA achieve its objective and is it cost-effective? This literature review tries to answer these challenging questions.

Keywords: abdominal aortic aneurysm; cost-effectiveness; follow-up; preventive medicine; screening program; ultrasound.

Publication types

  • Review

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Aortic Aneurysm, Abdominal / diagnostic imaging*
  • Aortic Aneurysm, Abdominal / economics
  • Aortic Aneurysm, Abdominal / mortality
  • Aortic Aneurysm, Abdominal / therapy
  • Aortic Rupture / diagnostic imaging*
  • Aortic Rupture / economics
  • Aortic Rupture / mortality
  • Aortic Rupture / therapy
  • Cost-Benefit Analysis
  • Early Diagnosis
  • Female
  • Health Care Costs
  • Humans
  • Life Expectancy
  • Male
  • Mass Screening / economics
  • Mass Screening / methods*
  • Middle Aged
  • Predictive Value of Tests
  • Prevalence
  • Prognosis
  • Risk Assessment
  • Risk Factors
  • Sex Factors
  • Ultrasonography* / economics