Scalable electrochemical oxidant-and metal-free dehydrogenative coupling of S-H/N-H

Shanyu Tang; Yan Liu; Longjia Li; Xuanhe Ren; Jiao Li; Guanyu Yang; Heng Li; Bingxin Yuan

doi:10.1039/c8ob03211d

Scalable electrochemical oxidant-and metal-free dehydrogenative coupling of S-H/N-H

Org Biomol Chem. 2019 Feb 6;17(6):1370-1374. doi: 10.1039/c8ob03211d.

Authors

Shanyu Tang¹, Yan Liu, Longjia Li, Xuanhe Ren, Jiao Li, Guanyu Yang, Heng Li, Bingxin Yuan

Affiliation

¹ Department of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China 450001. hengli@zzu.edu.cn bxyuan@zzu.edu.cn.

PMID: 30648724
DOI: 10.1039/c8ob03211d

Abstract

A practical and scalable electrochemical oxidation of S-H and N-H was developed. This oxidant- and catalyst-free electrochemical process enables S-N bond formation with inexpensive nickel electrodes in an undivided cell. This procedure exhibits broad substrate scopes and good functional-group compatibility. A 50 g scale oxidative coupling augurs well for industrial applications.

Publication types

Research Support, Non-U.S. Gov't