The board of the Society for Prevention Research noted recently that extant methods for the analysis of causality mechanisms in prevention may still be too rudimentary for detailed and sophisticated analysis of causality hypotheses. This Special Section aims to fill some of the current voids, in particular in the domain of statistical methods of the analysis of causal inference. In the first article, Bray et al. propose a novel methodological approach in which they link propensity score techniques and Latent Class Analysis. In the second article, Kelcey et al. discuss power analysis tools for the study of causal mediation effects in cluster-randomized interventions. Wiedermann et al. present, in the third article, methods of Direction Dependence Analysis for the identification of confounders and for inference concerning the direction of causal effects in mediation models. A more general approach to the identification of causal structures in non-experimental data is presented by Shimizu in the fourth article. This approach is based on linear non-Gaussian acyclic models. Molenaar introduces vector-autoregressive methods for the optimal representation of Granger causality in time-dependent data. The Special Section concludes with a commentary by Musci and Stuart. In this commentary, the contributions of the articles in the Special Section are highlighted from the perspective of the experimental causal research tradition.
Keywords: Causal mediation; Causal structure learning; Direction dependence analysis; Granger causality; Propensity score techniques.