Engineering Plant Secondary Metabolism in Microbial Systems

Michael E Pyne; Lauren Narcross; Vincent J J Martin

doi:10.1104/pp.18.01291

Engineering Plant Secondary Metabolism in Microbial Systems

Plant Physiol. 2019 Mar;179(3):844-861. doi: 10.1104/pp.18.01291. Epub 2019 Jan 14.

Authors

Michael E Pyne¹, Lauren Narcross¹, Vincent J J Martin²

Affiliations

¹ Department of Biology, Centre for Applied Synthetic Biology, Centre for Structural and Functional Genomics, Concordia University, Montreal, Quebec, Canada.
² Department of Biology, Centre for Applied Synthetic Biology, Centre for Structural and Functional Genomics, Concordia University, Montreal, Quebec, Canada vincent.martin@concordia.ca.

Abstract

An overview of common challenges and strategies underlying efforts to reconstruct plant isoprenoid, alkaloid, phenylpropanoid, and polyketide biosynthetic pathways in microbial systems.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkaloids / biosynthesis
Alkaloids / genetics
Biosynthetic Pathways
Escherichia coli / genetics
Escherichia coli / metabolism
Metabolic Engineering / trends*
Plants / genetics
Plants / metabolism*
Polyketides / metabolism
Saccharomyces cerevisiae / genetics
Saccharomyces cerevisiae / metabolism
Synthetic Biology*
Terpenes / metabolism

Substances

Alkaloids
Polyketides
Terpenes