Prevalence of Pathogenic Variants of FAN1 in More Than 5000 Patients Assessed for Genetic Predisposition to Colorectal, Breast, Ovarian, or Other Cancers

Gastroenterology. 2019 May;156(6):1919-1920. doi: 10.1053/j.gastro.2019.01.003. Epub 2019 Jan 9.
No abstract available

MeSH terms

  • Breast Neoplasms / genetics*
  • Codon, Nonsense
  • Colorectal Neoplasms / genetics*
  • Computational Biology
  • Endodeoxyribonucleases
  • Exodeoxyribonucleases / genetics*
  • Female
  • Frameshift Mutation
  • Genetic Predisposition to Disease*
  • Heterozygote
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Male
  • Multifunctional Enzymes
  • Ovarian Neoplasms / genetics*
  • Pedigree

Substances

  • Codon, Nonsense
  • Multifunctional Enzymes
  • Endodeoxyribonucleases
  • Exodeoxyribonucleases
  • FAN1 protein, human