Relapsed or refractory chronic lymphocytic leukemia retreated with rituximab in daily practice: final results of the PERLE study

Driss Chaoui; Maya Hacini; Olivier Fitoussi; Lionel Karlin; Yazid Arkam; Eric Jourdan; Hubert Orfeuvre; Laurent Voillat; Laurence Sanhes; Stéphane Leprêtre; Kun Lun Liu; Marly Barry; Adrian Tempescul; Marie-Sarah Dilhuydy; Abdelaziz Chaib; Borhane Slama; Jean Luc Labourey; Omar Benbrahim; Brigitte Dreyfus; Béatrice Mahé; Marc Maynadié; Alain Delmer; Chahinez Benkanoun; Frédéric Boissard; Sophie Gandon; Kalaivani Veerabudun; Sylvain Choquet; PERLE investigators

doi:10.1080/10428194.2018.1533130

Relapsed or refractory chronic lymphocytic leukemia retreated with rituximab in daily practice: final results of the PERLE study

Leuk Lymphoma. 2019 Jun;60(6):1563-1567. doi: 10.1080/10428194.2018.1533130. Epub 2019 Jan 9.

Authors

Driss Chaoui¹, Maya Hacini², Olivier Fitoussi³, Lionel Karlin⁴, Yazid Arkam⁵, Eric Jourdan⁶, Hubert Orfeuvre⁷, Laurent Voillat⁸, Laurence Sanhes⁹, Stéphane Leprêtre¹⁰, Kun Lun Liu¹¹, Marly Barry¹², Adrian Tempescul¹³, Marie-Sarah Dilhuydy¹⁴, Abdelaziz Chaib¹⁵, Borhane Slama¹⁶, Jean Luc Labourey¹⁷, Omar Benbrahim¹⁸, Brigitte Dreyfus¹⁹, Béatrice Mahé²⁰, Marc Maynadié²¹, Alain Delmer²², Chahinez Benkanoun²³, Frédéric Boissard²³, Sophie Gandon²³, Kalaivani Veerabudun²⁴, Sylvain Choquet²⁵; PERLE investigators

Affiliations

¹ a Department of Hematology , Victor Dupouy Hospital , Argenteuil , France.
² b Department of Hematology , Chambéry Hospital , Chambéry , France.
³ c Department of Hematology , Bordeaux Nord Clinic , Bordeaux, France.
⁴ d CHU Lyon Sud , Lyon , France.
⁵ e Department of Hematology , Émile Muller Hospital , Mulhouse , France.
⁶ f Department of Hematology , Nîmes University Hospital , Nîmes , France.
⁷ g Hospital Hematology, Centre Hospitalier de Fleyriat , Bourg en Bresse , France.
⁸ h CH William Morey , Châlon sur Saone , France.
⁹ i Department of Hematology , Saint-Jean Hospital , Perpignan , France.
¹⁰ j Department of Hematology , Henri Becquerel Hospital , Rouen , France.
¹¹ k Hautepierre Hospital , Strasbourg , France.
¹² l Department of Hematology , Dr Duchenne Hospital , Boulogne sur Mer , France.
¹³ m Department of Hematology , Auguste Morvan Hospital , Brest , France.
¹⁴ n Department of Hematology , Bordeaux Pessac Hospital, Haut Levêque Hospital , Pessac , France.
¹⁵ o CH Pays d'Aix , Aix en Provence , France.
¹⁶ p CH Henri Duffaut , Avignon , France.
¹⁷ q CH Carcassonne Antoine Gayraud , Carcassonne , France.
¹⁸ r Hopital La Source , La Source , France.
¹⁹ s Department of Hematology , Regional Oncology Center , Poitiers , France.
²⁰ t Department of Hematology , Nantes University Hospital , Nantes , France.
²¹ u Department of Hematology , Bocage University Hospital , Dijon , France.
²² v Department of Hematology , Robert Debré University Hospital , Reims , France.
²³ w Medical Affairs, Roche France , Boulogne-Billancourt , France.
²⁴ x Axial R&D , Boulogne-Billancourt , France.
²⁵ y Department of Hematology , La Pitié Salpêtrière Hospital , Paris , France.

PMID: 30624147
DOI: 10.1080/10428194.2018.1533130

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Agents, Immunological / therapeutic use*
Drug Resistance, Neoplasm
Female
France / epidemiology
Humans
Kaplan-Meier Estimate
Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy*
Leukemia, Lymphocytic, Chronic, B-Cell / epidemiology
Leukemia, Lymphocytic, Chronic, B-Cell / mortality
Leukemia, Lymphocytic, Chronic, B-Cell / pathology*
Male
Multicenter Studies as Topic
Recurrence
Retreatment
Rituximab / therapeutic use*
Treatment Outcome

Substances

Antineoplastic Agents, Immunological
Rituximab