Oncocytic and tall columnar type papillary thyroid carcinoma arising on a mature cystic teratoma: A case report and literature review

J Pak Med Assoc. 2019 Jan;69(1):116-119.

Abstract

Mature cystic teratoma (MCT) is the most common germ cell ovarian tumour, which accounts for 15-20% of all ovarian neoplasms. The frequency of MCT cases undergoing malignant transformation ranges from 0.17% to 2%. Our aim for presenting this case is to contribute to formation of an algorithm in the literature for the treatment and follow-up of MCT undergoing malignant transformation. A 38-year-old female patient presented to the emergency service with acute abdomen. The patient underwent salpingo-oophorectomy due to a prediagnosis of ovarian torsion with a dermoid cyst. Postoperative pathological examination reported oncocytic and tall columnar type papillary thyroid carcinoma arising on a mature cystic teratoma. During the follow up no local recurrences or metastases were identified in one-year. The rarity of MCT cases undergoing papillary type thyroid carcinoma transformation hinders the establishment of an algorithm for treatment and follow-up in literature.

Keywords: Mature cystic teratomas, Papillary thyroid carcinoma..

Publication types

  • Case Reports

MeSH terms

  • Abdomen, Acute / diagnosis*
  • Abdomen, Acute / etiology
  • Adult
  • Algorithms
  • Cell Transformation, Neoplastic / pathology*
  • Diagnosis, Differential
  • Female
  • Humans
  • Ovarian Neoplasms* / pathology
  • Ovarian Neoplasms* / physiopathology
  • Ovarian Neoplasms* / surgery
  • Patient Care Management / methods
  • Salpingo-oophorectomy / methods*
  • Teratoma* / pathology
  • Teratoma* / physiopathology
  • Teratoma* / surgery
  • Thyroid Cancer, Papillary* / pathology
  • Thyroid Cancer, Papillary* / physiopathology
  • Thyroid Cancer, Papillary* / surgery
  • Treatment Outcome