PTEN abnormalities predict poor outcome in children with T-cell acute lymphoblastic leukemia treated according to ALL IC-BFM protocols

Am J Hematol. 2019 Apr;94(4):E93-E96. doi: 10.1002/ajh.25396. Epub 2019 Jan 24.

Bronisława Szarzyńska-Zawadzka¹, Joachim B Kunz^{2

3

4}, Łukasz Sędek⁵, Maria Kosmalska¹, Katarzyna Zdon⁶, Przemysław Biecek⁶, Obul R Bandapalli^{2

3

4}, Monika Kraszewska-Hamilton¹, Roman Jaksik⁷, Monika Drobna¹, Jerzy R Kowalczyk⁸, Tomasz Szczepański⁹, Pieter Van Vlierberghe^{10

11}, Andreas E Kulozik^{2

3

4}, Michał Witt¹, Małgorzata Dawidowska¹

¹ Institute of Human Genetics, Polish Academy of Sciences, Poznań, Poland.
² Department of Pediatric Oncology, Hematology, and Immunology and Hopp Children's Cancer Center (KiTZ), University of Heidelberg, Heidelberg, Germany.
³ Molecular Medicine Partnership Unit, European Molecular Biology Laboratory, University of Heidelberg, Heidelberg, Germany.
⁴ German Consortium for Translational Cancer Research (DKTK), Heidelberg, Germany.
⁵ Department of Microbiology and Immunology, Medical University of Silesia, Katowice, Poland.
⁶ Faculty of Mathematics and Information Science, Warsaw University of Technology, Warsaw, Poland.
⁷ Silesian University of Technology, Gliwice, Poland.
⁸ Department of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, Lublin, Poland.
⁹ Department of Pediatric Hematology and Oncology, Zabrze, Medical University of Silesia, Katowice, Poland.
¹⁰ Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
¹¹ Cancer Research Institute Ghent (CRIG), Ghent, Belgium.

No abstract available

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