The Value of Ambulatory Urodynamics in the Evaluation of Treatment Effect of Sacral Neuromodulation

Urol Int. 2019;102(3):299-305. doi: 10.1159/000493988. Epub 2019 Jan 4.

Abstract

Objectives: To assess the improvement of symptoms by sacral neuromodulation (SNM) in an objective way by carrying out an ambulatory urodynamic study (ambulatory-UDS). Until now, successful treatment has been defined as a ≥50% improvement recorded on voiding diaries. Voiding diaries are a patient reported outcome tool. A tool with less bias is desired to evaluate the treatment results before an expensive permanent system is implanted.

Methods: Between 2002 and 2015, a total of 334 patients with lower urinary tract symptoms were included consecutively in an ambulatory-UDS database. From this database, a subgroup of patients was selected which underwent SNM.

Results: In 51 patients, an ambulatory-UDS was performed both at baseline and during the SNM test period. A positive treatment outcome after test stimulation based on the patients' voiding diary, correlated (p < 0.0001) with an improvement on ambulatory-UDS. Twenty-six of the 30 patients, who have showed improvement of more than 50% on voiding diary parameters and who had subjective improvement of their symptoms, showed an early improvement on ambulatory-UDS.

Conclusions: Ambulatory-UDS can be used in clinical decision making, as it is associated with voiding diary improvement during the SNM test period. Using ambulatory-UDS to confirm success could in the future justify the shortening of the test period.

Keywords: Ambulatory monitoring; Non-obstructive urinary retention; Overactive; Overactive bladder; Sacral neuromodulation; Underactive bladder; Urinary bladder; Urinary retention; Urodynamic study.

MeSH terms

  • Adult
  • Databases, Factual
  • Electric Stimulation Therapy
  • Female
  • Humans
  • Lumbosacral Plexus / pathology*
  • Male
  • Middle Aged
  • Monitoring, Ambulatory
  • Sacrum
  • Treatment Outcome
  • Urinary Bladder / pathology*
  • Urinary Bladder, Overactive / therapy*
  • Urinary Retention / therapy
  • Urination*
  • Urodynamics*
  • Urologic Surgical Procedures