Genetic data for PowerPlex 21™ autosomal and PowerPlex 23 Y-STR™ loci from population of the state of Uttar Pradesh, India

Int J Legal Med. 2019 Sep;133(5):1381-1383. doi: 10.1007/s00414-018-01993-z. Epub 2019 Jan 4.

Abstract

In the present study, the statistical forensic parameters were evaluated for the loci present in PowerPlex 21 autosomal and PowerPlex 23 Y-STR multiplex systems in 168 unrelated individuals living in the state of Uttar Pradesh, India. The combined discrimination power (CPD) and combined exclusion power (CPE) was 1 and 0.999999 respectively for all 20 autosomal STR loci. Penta E showed the greatest (0.980) and CSF1PO showed the lowest (0.855) power of discrimination in the studied population. The haplotype diversity for 23 Y-STR loci was observed to be 0.999. The study also presents the first global report on polymorphism on D1S1656, D6S1043 and D12S391 autosomal STR loci in the Indian population. The resulting data revealed that these STR multiplex systems are highly polymorphic and can be used for forensic purposes.

Keywords: Genetic distribution; Short tandem repeat; Uttar Pradesh, India.

MeSH terms

  • Adult
  • Chromosomes, Human, Pair 21 / genetics*
  • Chromosomes, Human, Y / genetics*
  • DNA Fingerprinting / methods
  • Databases, Genetic
  • Ethnicity / genetics*
  • Female
  • Forensic Genetics
  • Gene Frequency
  • Genetic Loci*
  • Genetics, Population / methods*
  • Haplotypes
  • Humans
  • India
  • Male
  • Microsatellite Repeats*
  • Polymorphism, Genetic
  • Sequence Analysis, DNA*