Diagnostic accuracy of synovial chondromatosis of the temporomandibular joint on magnetic resonance imaging

Xiaohan Liu; Shaonan Wan; Pei Shen; Yating Qiu; Manoj Kumar Sah; Ahmed Abdelrehem; Minjie Chen; Shanyong Zhang; Chi Yang

doi:10.1371/journal.pone.0209739

Diagnostic accuracy of synovial chondromatosis of the temporomandibular joint on magnetic resonance imaging

PLoS One. 2019 Jan 3;14(1):e0209739. doi: 10.1371/journal.pone.0209739. eCollection 2019.

Authors

Xiaohan Liu^{1

2}, Shaonan Wan², Pei Shen², Yating Qiu², Manoj Kumar Sah², Ahmed Abdelrehem³, Minjie Chen^{2

4}, Shanyong Zhang^{2

4}, Chi Yang^{2

4}

Affiliations

¹ College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
² Department of Oral Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
³ Department of Craniomaxillofacial and Plastic Surgery, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
⁴ Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology; National Clinical Research Center of Stomatology, Shanghai, China.

Abstract

The purpose of this study was to evaluate the diagnostic accuracy of magnetic resonance imaging (MRI) for synovial chondromatosis (SC) of the temporomandibular joint (TMJ). In this study, 1415 patients (2109 joints) with temporomandibular joint disorders were collected between January 2012 and January 2017. All patients had a preoperative MRI examination and were treated by either arthroscopy or open surgery. On reviewing all MRI images, the number of "positive", "suspicious", and "negative" cases was collected afterwards, then the number of reported SC cases in operative data was recorded. The SPSS software was used to process all collected data. The kappa coefficient and ROC curve (AUC-index) with sensitivity and specificity were calculated to evaluate the consistency between MRI and arthroscopy/open surgery. Compared to 156 joints with SC detected by arthroscopy and open surgery, the results of MRI examination showed "positive" in 117 joints, and "negative" in 1938 joints. The number of "true positive", and "true negative" cases was 95, and 1897 respectively. The AUC-index was 0.86 (0.82-0.90) with a kappa coefficient of 0.74 (P < 0.05). In conclusion, the incidence of synovial chondromatosis diagnosed on MRI was in accordance with the arthroscopic and open surgery. Therefore, being a relatively non-invasive tool, MRI could be recommended as an effective diagnostic modality for SC.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Aged
Arthroscopy / methods
China
Chondromatosis, Synovial / diagnostic imaging*
Female
Humans
Magnetic Resonance Imaging / methods*
Male
Middle Aged
ROC Curve
Retrospective Studies
Sensitivity and Specificity
Temporomandibular Joint / diagnostic imaging
Temporomandibular Joint / pathology*
Temporomandibular Joint Disorders / pathology

Grants and funding

This study was supported by the Youth Program of National Natural Science Foundation of China (grant 81601915 awarded to Pei Shen), Science and Technology Commission of Shanghai Funding/Supporting (16411960900), The New Frontier Technology Joint Research Project of Shanghai (grant SHDC12017101 awarded to Dr. Chi Yang) and Shanghai Summit & Plateau Disciplines, and the Municipality Science Research Project (grant JYLJ003 awarded to Dr. Chi Yang). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.