Storing Digital Information in the Long Read DNA

Genomics Inform. 2018 Dec;16(4):e30. doi: 10.5808/GI.2018.16.4.e30. Epub 2018 Dec 28.

Abstract

There is urgent need in effective and cost-efficient data storage as worldwide requirement of data storage rapidly growing. DNA has introduced a new tool for storing digital information. Recent studies successfully store digital information such as text and gif animation. Previous studies tackle technical hurdles due to errors from DNA synthesis and sequencing. Studies also have focused on the strategy which makes use of 100-150 bps of read size in both synthesis and sequencing. In this paper, we suggest novel data encoding / decoding scheme which makes use of long read DNA (~1,000bp). This enables accurate recovery of stored digital information with a smaller number of reads than previous approach. Also, the approach reduces sequencing time.

Keywords: DNA; Data storage; Information; Nanopore sequencing.