Aromatic compounds from Endocomia macrocoma

Nat Prod Res. 2020 Feb;34(3):390-397. doi: 10.1080/14786419.2018.1534851. Epub 2019 Jan 2.

Abstract

Twenty-seven compounds, including a new diarypropane and two new lignans were isolated from the twigs and leaves of Endocomia macrocoma. Their structures were elucidated by spectroscopic analysis. Cytotoxicity evaluation of the new compounds against five human tumor lines showed no inhibitory effects.[Formula: see text].

Keywords: Endocomia macrocoma; flavonoids; horsfielenidine; lignans.

MeSH terms

  • Cell Line, Tumor
  • Drug Screening Assays, Antitumor
  • Humans
  • Lignans / chemistry
  • Lignans / isolation & purification*
  • Lignans / pharmacology
  • Molecular Structure
  • Myristicaceae / chemistry*
  • Plant Extracts / chemistry
  • Plant Leaves / chemistry
  • Propane / chemistry
  • Propane / isolation & purification*
  • Propane / pharmacology

Substances

  • Lignans
  • Plant Extracts
  • Propane