The investigation of organochlorine pesticides (OCPs) levels in sea turtles is an important issue in conservation research, due to the harmful effects of these chemicals. In the present study, OCPs concentrations were determined in the eggs of two sea turtle species (Eretmochelys imbricata and Chelonia mydas) collected from the Punta Xen and Isla Aguada (Mexican coast) in 2014 and 2015. Concentrations of 20 OCPs were analysed, including isomers of hexachlorocyclohexane, aldrin, chlordanes, endosulfans, methoxychlor, DDTs, and heptachlor. From the group of contaminants considered (analysed as families), the results revealed higher concentrations of ΣHCH and ΣDienes on both selected species. We analysed the relationship between turtle size and the OCPs concentrations; no correlation was found between the size of the female and concentrations in the eggs. In addition, principal component analysis indicated pattern differences between species and years, in good agreement with concentrations differences.