Complexity of knee extensor torque in patients with frailty syndrome: a cross-sectional study

Abstract

Background: Frailty syndrome is characterized by a marked reduction in physiological reserves and a clinical state of vulnerability to stress. Torque complexity analysis could reveal changes in the musculoskeletal systems that are the result of having the syndrome.

Objective: The aim of this study was to evaluate the complexity of submaximal isometric knee extensor torque in frail, pre-frail, and non-frail older adults. A secondary aim was to analyze the torque complexity behavior in different force levels in each group.

Methods: A cross-sectional study was conducted. Forty-two older adults were divided into three groups: non-frail (n=15), pre-frail (n=15), and frail (n=12). The data collected included body composition, five times sit-to-stand test, walking speed, and isometric knee extensor torque at 15, 30, and 40% of maximal voluntary contraction. The knee extensor torque variability was evaluated by coefficient of variation, and the torque complexity was evaluated by approximate entropy and sample entropy.

Results: The frail group presented a reduction in body mass and peak torque value compared to the non-frail group. Also, the frail group showed worse physical performance (on the five times sit-to-stand test and walking speed) compared to the pre-frail and non-frail groups. In addition, the frail older adults showed reduced torque complexity compared to the non-frail group. Finally, the association between torque complexity and force levels remained similar in all groups.

Conclusion: Torque complexity is reduced in the presence of frailty syndrome.

Keywords: Aged; Complexity; Frailty; Muscle strength; Physical therapy.