Objective: To investigate the characteristics and clinical utility of vestibular autorotation test (VAT) in patients with vestibular migraine(VM). Methods: This study included two groups, a VM group (441 patients from Tianjin First Center Hospital between January 2015 and May 2016) and a control group (65 healthy subjects). Both groups undertook VAT; the parameters evaluated were horizontal gain/phase, vertical gain/phase and asymmetry. The differences in VAT results between the two groups were investigated. Results: There were statistically significant differences in VAT results between the VM and the control group, namely elevated horizontal gain at frequency 2, 3, 4 and 5 Hz, delay horizontal phase at frequency 2, 4, 5 and 6 Hz, elevated vertical gain at frequency 2-6 Hz and delay vertical phase at frequency 4-6 Hz. There was no significant difference in asymmetric values between the VM group and the control group. Conclusions: The results of this study indicate that VM patients have elevated horizontal gain and vertical gain, and delay horizontal phase and vertical phase. It is suggested that VAT represents a useful diagnostic tool which may provide objective evidence for the diagnosis and differential diagnosis of VM.
目的： 探讨前庭性偏头痛(vestibular migraine，VM)患者前庭自旋转试验(vestibular autorotation test，VAT)的特点及临床意义。 方法： 研究对象为2015年1月至2016年5月来自天津市第一中心医院的441例前庭性偏头痛患者(VM组)，其中男77例、女364例，年龄14～68岁，平均49岁；同期65名健康志愿者作为对照组，其中男34名、女31名，年龄17～62岁，平均44岁。两组受试者均进行VAT测试，以VAT水平及垂直增益和相位以及非对称性为观察指标，利用SPSS 16.0统计软件分析比较两组测试结果。 结果： 与对照组相比，VM组患者VAT水平及垂直增益均增高，其中2～5 Hz水平增益、2～6 Hz垂直增益差异有统计学意义(P值均<0.05)。与对照组相比，VM组的水平及垂直相位均有延迟，其中2、4、5、6 Hz的水平相位以及4～6 Hz的垂直相位，延迟差异有统计学意义(P值均<0.05)。VM组与对照组各个频率非对称值比较，差异均无统计学意义(P值均>0.05)。 结论： 前庭性偏头痛患者VAT的水平及垂直增益增高，伴随水平及垂直相位的延迟。VAT可为前庭性偏头痛患者的诊断提供客观依据并有助于其鉴别诊断。.
Keywords: Migraine disorders; Reflex, vestibulo-ocular; Vestibular autorotation test; Vestibular function tests.