Primary angiosarcoma of the femoral artery in patient with kidney and liver polycystosis and multiple arterial aneurysms: report of the case and review of the literature

Ondrej Fabian; Dana Mokra; Jan Masopust; Jiri Skorepa; Daniela Novakova Kodetova; Josef Zamecnik

doi:10.1016/j.carpath.2018.11.001

Primary angiosarcoma of the femoral artery in patient with kidney and liver polycystosis and multiple arterial aneurysms: report of the case and review of the literature

Cardiovasc Pathol. 2019 Mar-Apr:39:8-11. doi: 10.1016/j.carpath.2018.11.001. Epub 2018 Nov 30.

Authors

Ondrej Fabian¹, Dana Mokra², Jan Masopust², Jiri Skorepa³, Daniela Novakova Kodetova⁴, Josef Zamecnik⁴

Affiliations

¹ Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University and Motol University Hospital, V Uvalu 84, Prague, 5, 150 06, Czech Republic. Electronic address: ondrejfabian5@gmail.com.
² Department of Internal Medicine, 2nd Faculty of Medicine, Charles University and Motol University Hospital, V Uvalu 84, Prague, 5, 150 06, Czech Republic.
³ 3(rd) Department of Surgery, 1st Faculty of Medicine, Charles University and Motol University Hospital, V Uvalu 84, Prague, 5, 150 06, Czech Republic.
⁴ Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University and Motol University Hospital, V Uvalu 84, Prague, 5, 150 06, Czech Republic.

PMID: 30579128
DOI: 10.1016/j.carpath.2018.11.001

Abstract

The association between kidney and liver polycystosis and arterial aneurysms is well documented. However, it remains unclear whether these patients are at increased risk of malignant transformation. In this article, we describe a case of a primary angiosarcoma of the femoral artery with metastatic spread into the lungs and hilar lymph node arising in a 74-year-old man with kidney and liver polycystosis and multiple arterial aneurysms.

Keywords: Aneurysm; Angiosarcoma; Femoral artery; Polycystic kidney.

Publication types

Case Reports
Systematic Review

MeSH terms

Aged
Aneurysm / complications*
Aneurysm / diagnosis
Biomarkers, Tumor / analysis
Biopsy
Cysts / complications*
Cysts / diagnosis
Femoral Artery* / chemistry
Femoral Artery* / pathology
Hemangiosarcoma / chemistry
Hemangiosarcoma / complications*
Hemangiosarcoma / secondary
Humans
Immunohistochemistry
Liver Diseases / complications*
Liver Diseases / diagnosis
Lung Neoplasms / chemistry
Lung Neoplasms / complications*
Lung Neoplasms / secondary
Lymphatic Metastasis
Polycystic Kidney Diseases / complications*
Polycystic Kidney Diseases / diagnosis
Vascular Neoplasms / chemistry
Vascular Neoplasms / complications*
Vascular Neoplasms / pathology

Substances

Biomarkers, Tumor

Supplementary concepts

Polycystic liver disease