Defective glycosylation leads to defective gp130-dependent STAT3 signaling in PGM3-deficient patients

J Allergy Clin Immunol. 2019 Apr;143(4):1638-1640.e2. doi: 10.1016/j.jaci.2018.12.987. Epub 2018 Dec 19.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cytokine Receptor gp130 / metabolism*
  • Glycosylation
  • Humans
  • Phosphoglucomutase / deficiency*
  • Phosphoglucomutase / genetics
  • Primary Immunodeficiency Diseases / genetics*
  • Primary Immunodeficiency Diseases / immunology
  • Primary Immunodeficiency Diseases / metabolism
  • STAT3 Transcription Factor / metabolism*
  • Signal Transduction / immunology*

Substances

  • STAT3 Transcription Factor
  • STAT3 protein, human
  • Cytokine Receptor gp130
  • PGM3 protein, human
  • Phosphoglucomutase