Community case management of lower chest indrawing pneumonia with oral amoxicillin in children in Kenya

Acta Paediatr. 2018 Dec:107 Suppl 471:44-52. doi: 10.1111/apa.14405.

Abstract

Aim: To determine the accuracy and effectiveness of community health workers (CHWs) when compared to trained nurses for management of pneumonia in Kenyan children.

Methods: In Homabay County in western Kenya, children 2-59 months of age with lower chest indrawing pneumonia were identified, classified and treated by CHWs with oral amoxicillin (90 mg/kg per day) for five days at home. Trained nurses visited the child within 24 hours to verify diagnosis; and on day 4 and 14 to assess treatment outcomes.

Results: CHWs identified 1906 children with lower chest indrawing pneumonia. There was an 88.7% concordance in classification and treatment for lower chest indrawing pneumonia by CHWs compared to nurses. Children with moderate malnutrition (OR 1.68; 95% CI: 1.22-2.30), comorbidities such as diarrhoea or malaria (OR 1.55; 95% CI: 1.32-1.81) or an additional day of delay in care seeking (OR 1.06; 95% CI: 1.02-1.10) were more likely to have an incorrect classification of lower chest indrawing by the CHW. Comorbidity (OR 1.66; 95% CI: 1.12-2.48) and fast breathing (OR 4.66; 95% CI: 1.26-17.27) were significantly associated with treatment failure on day 14.

Conclusion: CHWs can correctly manage lower chest indrawing pneumonia even in high-mortality settings, such as western Kenya, in sub-Saharan Africa.

Keywords: Chest indrawing; Community health workers; Integrated community case management; Pneumonia; Sub-Saharan Africa.

Publication types

  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amoxicillin / therapeutic use*
  • Anti-Bacterial Agents / therapeutic use*
  • Child, Preschool
  • Community Health Workers / statistics & numerical data*
  • Female
  • Health Plan Implementation
  • Humans
  • Infant
  • Kenya / epidemiology
  • Male
  • Pneumonia / diagnosis
  • Pneumonia / drug therapy*
  • Pneumonia / epidemiology

Substances

  • Anti-Bacterial Agents
  • Amoxicillin

Associated data

  • ANZCTR/ACTRN12614000208606