Successful treatment of congenital chylothorax with skimmed milk and long course octreotide

BMJ Case Rep. 2018 Dec 3;11(1):bcr2018226347. doi: 10.1136/bcr-2018-226347.

Abstract

Congenital chylothorax (CC) is a rare entity in neonatal period requiring multimodal management strategies. Despite optimum treatment, some cases remain refractory posing significant challenge to the treating physician. We here describe a 33-week preterm neonate presenting with refractory congenital chylothorax who needed treatment with combination of skimmed milk, high dose and prolonged duration octreotide for resolution. This case highlighted that octreotide has a good safety profile in newborn infants with congenital chylothorax and locally available skimmed milk fortified with medium chain triglyceride (MCT) oil is a cheap and safe alternative.

Keywords: Drugs: Gastrointestinal System; Lipid Disorders; Neonatal Intensive Care; Nutrition.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Chylothorax / congenital*
  • Chylothorax / diet therapy
  • Chylothorax / drug therapy
  • Diagnosis, Differential
  • Female
  • Gastrointestinal Agents / administration & dosage
  • Gastrointestinal Agents / therapeutic use
  • Humans
  • Infant
  • Infant, Premature*
  • Milk*
  • Octreotide / administration & dosage
  • Octreotide / therapeutic use

Substances

  • Gastrointestinal Agents
  • Octreotide

Supplementary concepts

  • Chylothorax, congenital