Inaccurate Multilocus Sequence Typing of Acinetobacter baumannii

Emerg Infect Dis. 2019 Jan;25(1):186-187. doi: 10.3201/eid2501.180374.

Abstract

Multilocus sequence typing has been useful for genotyping pathogens in surveillance and epidemiologic studies. However, it cannot reflect the true relationships of isolates for species with very dynamic genomes. Using a robust genome phylogeny, we demonstrated the limitations of this method for typing Acinetobacter baumannii.

Keywords: Acinetobacter baumannii; MLST; bacteria; genome sequencing; genotyping; multilocus sequence typing.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter Infections / microbiology*
  • Acinetobacter baumannii / classification*
  • Acinetobacter baumannii / genetics
  • Acinetobacter baumannii / isolation & purification
  • Bacterial Typing Techniques
  • Genome, Bacterial / genetics*
  • Genotyping Techniques
  • Humans
  • Multilocus Sequence Typing
  • Phylogeny