Two photon excitable graphene quantum dots for structured illumination microscopy and imaging applications: lysosome specificity and tissue-dependent imaging

Chem Commun (Camb). 2019 Jan 3;55(4):521-524. doi: 10.1039/c8cc08610a.

Abstract

Biocompatible graphene quantum dots (GQDs), obtained from extracts of neem root, are found to be suitable for structured illumination microscopy and two-photon microscopy (TPM). Results of TPM and confocal luminescence microscopy ensure lysosome specificity in live cells and tissue-dependent localization in zebrafish, respectively, of GQDs.

MeSH terms

  • Animals
  • Azadirachta / chemistry
  • Biocompatible Materials / chemistry*
  • Biocompatible Materials / isolation & purification
  • Graphite / chemistry*
  • Graphite / isolation & purification
  • Humans
  • Lysosomes / chemistry
  • MCF-7 Cells
  • Mice
  • Microscopy, Confocal
  • Microscopy, Fluorescence
  • Molecular Structure
  • Optical Imaging*
  • Photons*
  • Plant Extracts / chemistry
  • Plant Extracts / isolation & purification
  • Plant Roots / chemistry
  • Quantum Dots / chemistry*
  • RAW 264.7 Cells
  • Zebrafish

Substances

  • Biocompatible Materials
  • Plant Extracts
  • Graphite