[Selective laser trabeculoplasty in African blacks]

J Fr Ophtalmol. 2019 Jan;42(1):44-48. doi: 10.1016/j.jfo.2018.02.018. Epub 2018 Dec 10.
[Article in French]

Abstract

Introduction: The treatment of primary open angle glaucoma (POAG) is preferably medical. However, when medical therapy fails, alternative or complementary treatments may be considered. In this regard, selective laser trabeculoplasty is a widely popular procedural treatment whose accepted benefits have been very little studied in African blacks. The objective of this study was to assess the efficacy of selective laser trabeculoplasty on the reduction of intraocular pressure (IOP) in African blacks with POAG.

Methods: We conducted a retrospective study of black patients treated with selective laser trabeculoplasty between March 2010 and March 2011. All patients had POAG with trabecular meshwork accessible over 360°. The treatment protocol consisted of a 360°treatment in two sessions (180°/session) 15 days apart. Success was defined as decrease from the initial IOP≥3mm Hg without additional medications.

Results: We included 44 patients, corresponding to 82 eyes. The mean age of the patients was 55.94±11.66 years with extremes of 19 years and 76 years. The mean intraocular pressure before laser treatment (initial IOP) was 18.43±4.81mm Hg. After laser treatment, the mean pressure reduction was (i) 3.81mm Hg (20.67%) at 15 days ; (ii) 4.08mm Hg (22.14%) at 1 month; (iii) 4.45mm Hg (24.14%) at 3 months; and (iv) 4.95mm Hg (26.86%) at 6 months. The success rate after laser treatment was 67.60% at 15 days, 83.78% at 1 month, 72.09% at 3 months and 80.43% at 6 months.

Conclusion: Selective laser trabeculoplasty is effective in African blacks. Its efficacy is comparable to that of a carbonic anhydrase inhibitor or even a prostaglandin. It could be a complementary or substitutive alternative to POAG medications in African blacks.

Keywords: African blacks; Glaucome primitif à angle ouvert; Mélanoderme africain; Primary open angle glaucoma; Selective laser trabeculoplasty; Trabéculoplastie sélective.

MeSH terms

  • Adult
  • Aged
  • Black People* / statistics & numerical data
  • Female
  • Glaucoma, Open-Angle / ethnology*
  • Glaucoma, Open-Angle / surgery*
  • Humans
  • Laser Therapy / methods*
  • Laser Therapy / statistics & numerical data
  • Male
  • Middle Aged
  • Retrospective Studies
  • Trabeculectomy / methods*
  • Trabeculectomy / statistics & numerical data
  • Treatment Outcome
  • Young Adult