Controversies in Screening and Diagnostic Criteria for Gestational Diabetes in Early and Late Pregnancy

Evelyn A Huhn; Simona W Rossi; Irene Hoesli; Christian S Göbl

doi:10.3389/fendo.2018.00696

Controversies in Screening and Diagnostic Criteria for Gestational Diabetes in Early and Late Pregnancy

Front Endocrinol (Lausanne). 2018 Nov 27:9:696. doi: 10.3389/fendo.2018.00696. eCollection 2018.

Authors

Evelyn A Huhn¹, Simona W Rossi², Irene Hoesli¹, Christian S Göbl³

Affiliations

¹ Department of Obstetrics and Gynaecology, University Hospital Basel, Basel, Switzerland.
² Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland.
³ Division of Obstetrics and Feto-Maternal Medicine, Department of Obstetrics and Gynaecology, Medical University of Vienna, Vienna, Austria.

Abstract

This review serves to evaluate the screening and diagnostic strategies for gestational diabetes and overt diabetes in pregnancy. We focus on the different early screening and diagnostic approaches in first trimester including fasting plasma glucose, random plasma glucose, oral glucose tolerance test, hemoglobin A1c, risk prediction models and biomarkers. Early screening for gestational diabetes is currently not recommended since the potential benefits and harms of early detection and subsequent treatment need to be further evaluated in randomized controlled trials.

Keywords: diagnostic criteria; early biomarkers; gestational diabetes (GDM); pregnancy; screening.

Publication types

Review