Sclerosis of the arytenoid cartilage and glottic carcinoma: A clinical-pathological study

Head Neck. 2019 Jan;41(1):72-78. doi: 10.1002/hed.25372. Epub 2018 Dec 7.

Abstract

Background: Given the relevance of any tumor invasion of the arytenoid cartilage or crico-arytenoid unit to the planning open partial horizontal laryngectomy (OPHL) for laryngeal squamous cell carcinoma (LSCC), it is important to have a reliable radiological test to assess impairments of these structures.

Methods: We retrospectively compared the endoscopic, radiological, and pathological findings in patients with glottic LSCC who underwent OPHL.

Results: The endoscopic finding of a reduced (impaired or absent) vocal cord motility proved more sensitive, with better positive and negative predictive values, but less specific than the radiological finding of complete arytenoid sclerosis in detecting histologically assessable infiltration of the arytenoid cartilage.

Conclusions: Endoscopy retains a key role in the preoperative workup for glottic LSCC. CT evidence of complete sclerosis of the arytenoid cartilage is related to a dangerous contiguity of the tumor to the cartilage.

Keywords: arytenoid; infiltration; motility; partial laryngectomy; sclerosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arytenoid Cartilage / diagnostic imaging*
  • Arytenoid Cartilage / pathology*
  • Carcinoma, Squamous Cell / complications*
  • Carcinoma, Squamous Cell / surgery
  • Contrast Media
  • Female
  • Humans
  • Laryngeal Neoplasms / complications*
  • Laryngeal Neoplasms / surgery
  • Laryngectomy
  • Laryngoscopy
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Retrospective Studies
  • Sclerosis / diagnosis*
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed

Substances

  • Contrast Media