Interval-coded texture features for artifact rejection in automated cervical cytology

Cytometry. 1988 Sep;9(5):418-25. doi: 10.1002/cyto.990090503.

Abstract

In order to improve the separation between abnormal cells and noncellular artifacts in the CERVIFIP automated cervical cytology prescreening system, 22 different object texture features were investigated. The features were all statistical parameters of the pixel density histograms or one-dimensional filtered values of central and border regions of the object images. The features were calculated for 231 images (100 cells and 131 artifacts) detected as Suspect Cells by the current CERVIFIP and were then tested in hierarchical and linear discriminant classifiers. After selecting the two best features for use in a hierarchical classifier, 83% correct classification was achieved. One of these features was specifically designed to remove poorly focused objects. With maximum likelihood discrimination using all 22 features, an overall correct classification rate of 90% was obtained.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Division
  • Cytological Techniques*
  • DNA, Neoplasm / analysis*
  • Diagnosis, Computer-Assisted / methods*
  • Female
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Uterine Cervical Neoplasms / analysis*
  • Uterine Cervical Neoplasms / pathology

Substances

  • DNA, Neoplasm