Immunobiology of monocytes and macrophages during Chlamydia trachomatis infection

Mads Lausen; Gunna Christiansen; Thomas Bouet Guldbæk Poulsen; Svend Birkelund

doi:10.1016/j.micinf.2018.10.007

Immunobiology of monocytes and macrophages during Chlamydia trachomatis infection

Microbes Infect. 2019 Mar;21(2):73-84. doi: 10.1016/j.micinf.2018.10.007. Epub 2018 Dec 8.

Authors

Mads Lausen¹, Gunna Christiansen², Thomas Bouet Guldbæk Poulsen³, Svend Birkelund³

Affiliations

¹ Department of Health Science and Technology, Aalborg University, Fredrik Bajers Vej 3b, 9220 Aalborg Ø, Denmark. Electronic address: mln@hst.aau.dk.
² Department of Biomedicine, Aarhus University, Wilhelms Meyers Allé 4, 8000 Aarhus, Denmark.
³ Department of Health Science and Technology, Aalborg University, Fredrik Bajers Vej 3b, 9220 Aalborg Ø, Denmark.

PMID: 30528899
DOI: 10.1016/j.micinf.2018.10.007

Abstract

Infections caused by the intracellular bacterium Chlamydia trachomatis are a global health burden affecting more than 100 million people annually causing damaging long-lasting infections. In this review, we will present and discuss important aspects of the interaction between C. trachomatis and monocytes/macrophages.

Keywords: Chlamydia trachomatis; Macrophages; Monocytes.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Chlamydia Infections / immunology*
Chlamydia Infections / microbiology
Chlamydia trachomatis / immunology*
Humans
Macrophages / immunology
Macrophages / microbiology
Monocytes / immunology
Monocytes / microbiology