Nimodipine

Excerpt

Nimodipine is a second-generation 1,4-dihydropyridine calcium channel blocker that was originally approved by the FDA to manage hypertension. Today, nimodipine is predominantly used to manage vasospasm subsequent to subarachnoid hemorrhage, in addition to off-label applications. Nimodipine is available in various formulations, including oral tablets, solutions, and intravenous infusions. This discussion will primarily focus on this medication's administration methods and associated considerations. Equally important are the indications, mechanisms of action, adverse effects, contraindications, and monitoring associated with nimodipine administration. Healthcare professionals must have a deep comprehension of this medication in order to use it effectively. This informed decision-making not only optimizes dosage regimens but also mitigates adverse reactions, facilitating enhanced patient outcomes in subarachnoid hemorrhage scenarios treated with nimodipine.