Extracting Interesting Rules from Gestation Course Data for Early Diagnosis of Neonatal Hypoxia

J Med Syst. 2018 Dec 1;43(1):8. doi: 10.1007/s10916-018-1125-0.

Abstract

The topic of neonatal hypoxia is of paramount importance to anyone who cares during pregnancy and childbirth. Modern medicine associates this pathology with severe problems in the prenatal period. Underlying diseases of the mother during pregnancy, her anamnesis of life are the leading causes of complications in the newborn. Nevertheless, patterns of fetal hypoxia and neonatal hypoxia, as well as mechanisms of hypoxic-ischemic encephalopathy in newborns, remains poorly known and require further research. This study is focused on finding risk factors related to the chronic fetal hypoxia and defining a group of signs for diagnosing neonatal hypoxia. The real data of 186 pregnant women at the gestation age from 12 to 38 weeks were analyzed. A methodology for discovering interesting associations in gestation course data is proposed. Technique for association rules mining and rules selection by the neonatal hypoxia under study is discussed. The rules suggest that a strong relationship exists between the specific sets of attributes and the diagnosis. As a result, we set up a profile of the pregnant woman with a high likelihood of hypoxia of the newborn that would be beneficial to medical professionals.

Keywords: Gestation course data; Measure of interestingness; Mining association rules; Neonatal hypoxia.

MeSH terms

  • Algorithms
  • Data Collection / methods
  • Delivery, Obstetric
  • Early Diagnosis*
  • Female
  • Gestational Age*
  • Humans
  • Hypoxia / diagnosis*
  • Infant, Newborn
  • Pregnancy