Cu-Catalyzed Decarboxylative Borylation

ACS Catal. 2018 Oct 5;8(10):9537-9542. doi: 10.1021/acscatal.8b02928. Epub 2018 Sep 13.

Abstract

A simple method for the conversion of carboxylic acids to boronic esters via redox-active esters (RAEs) is reported using copper catalysis. The scope of this transformation is broad, and compared with the known protocols available, it represents the most inexpensive, rapid, and operationally simple option. In addition to a full exploration of the scope, a kinetic study was performed to elucidate substrate and reagent concentration dependences.