Abstract
A series of 3,4-bis(arylthio)maleimides were synthesized and their antimicrobial activity was evaluated against Gram-positive and Gram-negative bacteria, including multidrug resistant (MDR) strains and some fungi. Most compounds turned out to be highly active, activity being dependent on substituents on phenyl rings.
MeSH terms
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Anti-Bacterial Agents / chemical synthesis
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Anti-Bacterial Agents / pharmacology*
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Drug Resistance, Multiple, Bacterial / genetics
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Gram-Negative Bacteria / drug effects*
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Gram-Negative Bacteria / genetics
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Gram-Negative Bacteria / growth & development*
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Gram-Positive Bacteria / drug effects*
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Gram-Positive Bacteria / genetics
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Gram-Positive Bacteria / growth & development*
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Maleimides / chemical synthesis
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Maleimides / pharmacology*
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Microbial Sensitivity Tests
Substances
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Anti-Bacterial Agents
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Maleimides