Technologies to Augment Rotator Cuff Repair

Anand M Murthi; Manesha Lankachandra

doi:10.1016/j.ocl.2018.08.005

Technologies to Augment Rotator Cuff Repair

Orthop Clin North Am. 2019 Jan;50(1):103-108. doi: 10.1016/j.ocl.2018.08.005.

Authors

Anand M Murthi¹, Manesha Lankachandra²

Affiliations

¹ Department of Orthopaedics, MedStar Union Memorial Hospital, 3333 North Calvert Street, Suite 400, Baltimore, MD 21218, USA. Electronic address: amurthi14@hotmail.com.
² Department of Orthopaedics, MedStar Union Memorial Hospital, 3333 North Calvert Street, Suite 400, Baltimore, MD 21218, USA.

PMID: 30477699
DOI: 10.1016/j.ocl.2018.08.005

Abstract

Healing rates after rotator cuff repair vary widely. New technologies seek to improve tendon to bone healing with the addition of platelet-rich plasma, stem cells, and biological and synthetic grafts. Platelet-rich plasma and mesenchymal stem cells are used to help create a favorable environment for tendon to bone healing, and grafts and scaffolds provide structural support for repair. The efficacy of platelet-rich plasma and stem cell products seems to be variable, with different products offering different levels of cytokine and growth factors. Scaffold material is also variable with a wide range of synthetic and biological grafts.

Keywords: Allograft scaffold; Platelet-rich plasma; Rotator cuff repair; Stem cells; Synthetic scaffold.

Publication types

Meta-Analysis
Review

MeSH terms

Humans
Mesenchymal Stem Cell Transplantation / methods*
Rotator Cuff / surgery*
Rotator Cuff Injuries / surgery*
Tissue Engineering / methods*
Tissue Scaffolds*
Wound Healing