Reactive oxygen metabolites in alpha-herpesvirus-seropositive Mediterranean buffaloes (Bubalus bubalis): a preliminary study

Pol J Vet Sci. 2018 Sep;21(3):639-642. doi: 10.24425/124300.

Abstract

In the present study on Bubalus bubalis of the Campania Region (Italy) the serum levels of derivatives of reactive oxygen metabolites (d-ROMs), anti-ROM and oxidative stress index (Osi) were evaluated. These data were then related to the seropositive status of the animals against alpha-herpesviruses, precisely Bubaline herpesvirus 1 (BuHV-1) and Bovine herpesvirus 1 (BoHV-1). Clinically healthy Mediterranean buffaloes were selected for this study. The serum samples of these animals were taken, and d-ROMs, anti-ROM and Osi were measured using commercially available tests. The preliminary data demonstrated that animals seropositive to both BuHV-1 and BoHV-1 present more oxidative stress than seronegative animals, as revealed by a significant increase in d-ROMs. Our results provide, for the first time, insight into the reac- tive oxygen species (ROS) modulation induced by the herpesvirus in Bubalus bubalis.

Keywords: Bovine herpesvirus 1 (BoHV-1); Bubaline herpesvirus 1 (BuHV-1); Bubalus bubalis; oxidative stress index (Osi); reactive oxygen metabolites (ROM).

MeSH terms

  • Alphaherpesvirinae / immunology*
  • Animals
  • Buffaloes / blood*
  • Herpesviridae Infections / blood
  • Herpesviridae Infections / immunology
  • Herpesviridae Infections / metabolism
  • Herpesviridae Infections / veterinary*
  • Reactive Oxygen Species
  • Seroepidemiologic Studies

Substances

  • Reactive Oxygen Species