Helping Patients with Gastroparesis

Frances U Onyimba; John O Clarke

doi:10.1016/j.mcna.2018.08.013

Helping Patients with Gastroparesis

Med Clin North Am. 2019 Jan;103(1):71-87. doi: 10.1016/j.mcna.2018.08.013.

Authors

Frances U Onyimba¹, John O Clarke²

Affiliations

¹ Department of Medicine, Division of Gastroenterology, University of California San Diego, 9500 Gillman Drive, #0956, La Jolla, CA 92093, USA.
² Department of Medicine, Division of Gastroenterology and Hepatology, Stanford University, 300 Pasteur Drive, MC 5244, Stanford, CA 94305, USA. Electronic address: john.clarke@stanford.edu.

PMID: 30466677
DOI: 10.1016/j.mcna.2018.08.013

Abstract

Gastroparesis is an increasing concern and options remain limited. Diagnosis hinges on recognition of delayed gastric emptying in the absence of mechanical obstruction. Nontransit studies evaluating gastric motility serve a complementary role and may help guide therapy. Treatment consists of a combination of lifestyle and dietary medication, medications (antiemetics, prokinetics, neuromodulators, and accommodation-enhancers), alternative and complementary therapy, endoscopic therapy (pyloric-directed therapy, temporary stimulation, jejunostomy, or venting gastrostomy) and surgical therapy (pyloroplasty, gastric electrical stimulation, gastrectomy). Treatment can be tailored to the individual needs and symptoms of the affected patient.

Keywords: Gastric electrical stimulation; Gastroparesis; Nausea; Prokinetics; Vomiting.

Publication types

Review

MeSH terms

Complementary Therapies / methods
Diet / methods
Electric Stimulation Therapy / methods
Endoscopy, Gastrointestinal / methods
Female
Gastrectomy / methods
Gastrointestinal Agents / therapeutic use
Gastroparesis / diagnosis
Gastroparesis / therapy*
Humans
Life Style
Male
Stomach / physiopathology

Substances

Gastrointestinal Agents